Round 8 has come and gone…
This round was more or less similar to previous rounds, so in all honesty, there is very little to report. Nausea was the same and tiredness perhaps a little worse. I have cut my dexamethasone right back now, which has definite advantages on the side effects. I also played around with the nozinan (the antipsychotic) in order to try and reduce the amount of tiredness it gave me. I will likely play around with it a bit more next round, because I more or less spent all of Sunday sleeping. I’m almost certain that that is due to the nozinan primarily. I have to say though, it gives me a whole new sympathy for mental health patients that have to take the full dose of antipsychotics, the side effects are not that pleasant!
So that was round 8 done and dusted. Although it has to be said, that just because I return to work does not mean the effects of chemo are over. One of the longer standing effects from round 7 was chronic low grade lower abdominal pain that didn’t really properly clear up until 2 days before the next round of chemo. I am also still shedding hair like a cat and the dark rings under my eyes are less than appealing.
I’m now starting to seriously look at hair/hat solutions as the thinning is starting to look a little ridiculous, and also a bit fluffy….
I thought i would do a quick post giving a run down on the drugs that I’m currently on. The first on the list is the main event.
Capecitabine is the drug that i have to take 4 tablets (2gm) twice a day every 12 hours. This is a 5-flurouracil prodrug. The prodrug part means it gets metabolised into the active parts of the drug at the location of action, the idea being that it reduces the overall side effects. 5-FU is a DNA base analogue that gets incorporated into the DNA of rapidly dividing cells (namely the cancer cells) and then prevents them from dividing and growing further. This stuff is so toxic that 5 have to wash my hands after handling the the tablets.
Loperimide is the next drug in the lineup. This is essentially just an anti-diarrhoea drug, one of the main side-effects of Capecitabine.
Ondansatron is one of the best, and most expensive anti-emetics around, so much so that I can only get a script for this bad boy for no more than 6 a month.. so I have to use is sparingly……
Domperidone is another anti-emetic, that i take 2 tabs of 4 times a day, usually half an hour before each meal, then before bed.
Dexamethasone is a really really potent steroid, and will make me fat fast if I’m not careful. Its also a really really good anti-emetic, although its mechanism of action isn’t really known. They just know it works really well. This one is 2 tabs per day after breakfast.
And Finally, Paracetamol is just a good run-of-the-mill drug, it makes me sleep better at night, and helps with all the aches and pains the come with cramping all the time with the Capecitabine.
So there was a quick rundown on what Chemo involves. And don’t forget the 2 hour infusion of Oxaliplatin that I get at the beginning as well.